RNA Details
Disease Name
lupus erythematosus cutaneous
Tissue
skin
RNA Symbol
mir-31
RNA ID
RNA Type
miRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
immunofluorescence; flow cytometry etc.
Target
PEROXISOME PGC-1A
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
Title
MicroRNA Expression Profiling Identifies miR-31 and miR-485-3p as Regulators in the Pathogenesis of Discoid Cutaneous Lupus
Year
2019
Function
Our findings suggest that overexpression of mir-31 and mir-485-p contribute to skin inflammation in dle lesions by regulating the production of inflammatory mediators and attracting neutrophils and intermediate monocytes to the skin.